Alzheimer’s May Trigger Cell Death Mechanism
Researchers at a major U.S. biotech companies have discovered a new route through which the disease in May, either to start or sustain the destruction of brain cells: the mechanism that diverts is normally used for brain cells prune undesirable in early development and involves a part of unsuspected culprit known, APP, the precursor of amyloid plaques in the brains of people with Alzheimer’s disease disease.On information the authors explain that scientists have already discovered there are natural mechanisms by which adverse axons and neurons are pruned and killed with “sculpt neuronal connections during development, but exactly how they are still somewhat of a mystery.
In this study, researchers found that beta-amyloid precursor protein (APP) and death receptor 6 (DR6, also known as TNFRSF21) a broad program of self-destruction based on caspases (sometimes called “executioner proteins” because of their role in apoptosis or programmed cell death).